Clinical Project Manager – US

Senior Project Manager, Clinical Trials – REMOTE (U.S. Based)

Global CRO | Neuroscience-Focused | Permanent Role

Base: $125K–$140K + 401k Match + Full Benefits

The Opportunity:

We’re working with a global, tech-enabled CRO that’s transforming the way cognitive function is measured in clinical research and healthcare. With their digital assessment platform deployed in over 150 countries and across 2,000+ clinical trials, this organization is at the forefront of accelerating breakthroughs in neurology and brain health.

They’re hiring a Senior Project Manager with strong clinical trial experience to oversee complex, multinational studies and internal innovation projects. This is a strategic, client-facing role that blends traditional project management with exposure to digital health tools, cross-functional collaboration, and clinical operations leadership.

If you’ve led full-service studies, enjoy managing high-profile sponsor portfolios, and thrive in an agile, mission-driven environment—this could be a perfect fit.

Role Highlights:

• Own and lead the delivery of global clinical trials from Start-Up through Close-Out.
• Act as the primary sponsor point of contact, managing both individual studies and broader portfolios.
• Coordinate across internal teams (tech, ops, clinical, data science) to ensure on-time, on-budget delivery.
• Proactively identify and manage risks, solve problems, and guide teams through challenges.
• Oversee project financials: forecasting, invoicing, budget tracking, and change orders.
• Support proposal development for key accounts and work closely with business development.
• Drive internal innovation by leading process improvement initiatives and technology rollouts.
• Mentor junior team members and potentially step into line management responsibilities.
• Represent the company at investigator meetings and support sponsor audits as needed.

Ideal Candidate:

• 7+ years of clinical project management experience within a CRO, biotech, or pharmaceutical environment.
• Strong working knowledge of the drug development lifecycle and regulatory expectations.
• Bachelor’s degree in a scientific, technical, or healthcare field (e.g., Psychology, Biology, Nursing). Master’s or PMP certification a plus.
• Proven ability to manage global, multi-phase trials and engage cross-functional teams.
• Comfortable with Agile methodologies, digital health technologies, and clinical operations.
• Excellent communication and stakeholder management skills, including issue resolution.
• Experienced in project budgeting, invoicing, and financial oversight.
• Previous supervisory or mentorship experience preferred.

What’s In It For You:

• Remote-first flexibility across the U.S.
• High-impact role with real influence on patient outcomes and clinical innovation.
• Diverse global team working at the intersection of science, data, and technology.
• Culture focused on collaboration, continuous learning, and real-world impact.

Compensation & Benefits:

• Base Salary: $125,000 – $140,000 USD
• 401(k) match up to 3%
• Comprehensive medical, dental & vision benefits (plus free vision)
• 100% employer-paid short- and long-term disability & life insurance
• 30 days of total PTO (20 vacation, 10 personal) + 10 paid holidays
• Learning & development support for certifications, upskilling, and mentorship

This is a rare opportunity to join a purpose-driven, neuroscience-focused CRO that blends clinical rigor with innovation. If you’re a senior-level PM ready to take ownership of global studies and make a lasting impact—let’s talk.