Job Title: Clinical Trial Manager – Oncology
Location: San Francisco (Preferred)
Reports to: Director, Clinical Operations
Position Type: Full-Time
Salary Range: $130,000 – $160,000
About Us
We are a forward-thinking, early-stage biotech company focused on developing innovative therapies for cancer. With two promising programs in Phase I and Phase II trials, we are building a team dedicated to science, clinical excellence, and improving patient outcomes.
About the Role
We’re looking for an experienced Clinical Trial Manager (CTM) to lead early-phase oncology clinical trials. You’ll play a key role in planning, managing, and delivering high-quality studies from start to finish. If you’re passionate about oncology and thrive in a fast-paced biotech environment, we’d love to meet you.
What You’ll Do
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Oversee all aspects of Phase I–II clinical trials, including planning, execution, and timeline management.
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Act as the main contact for CROs, vendors, and clinical sites. Monitor performance and ensure compliance with study protocols and Good Clinical Practice (GCP).
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Prepare and maintain essential study documents (protocols, ICFs, CRFs, monitoring plans, etc.).
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Lead site start-up efforts—feasibility assessments, site selection, contract and budget negotiation.
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Work closely with cross-functional teams (data management, regulatory, medical, pharmacovigilance) to ensure smooth trial execution.
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Track study progress, identify risks early, and develop mitigation plans.
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Review clinical data, contribute to study reports, and support regulatory submissions.
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Ensure compliance with FDA regulations, ICH-GCP guidelines, and ethical standards.
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Help shape the clinical development strategy as programs advance.
What We’re Looking For
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Bachelor’s degree in life sciences or a related field (Master’s or higher preferred).
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5+ years of experience in clinical trial management, with at least 3 years in oncology and early-phase trials.
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Prior experience in a start-up or small biotech environment is a plus.
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Deep understanding of GCP, FDA regulations, and clinical trial operations.
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Strong skills in managing CROs and third-party vendors.
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Able to work independently in a lean, fast-moving team.
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Excellent communication, organization, and problem-solving abilities.
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Willingness to travel up to 25%.
Why Join Us?
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Be part of a mission-driven company focused on advancing cancer therapies.
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Work on cutting-edge clinical programs with real potential to transform care.
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Enjoy a collaborative, entrepreneurial team where your voice matters.
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Competitive salary, equity, and a comprehensive benefits package.
Ready to make a difference in oncology? Apply now and join us in shaping the future of cancer treatment.